納豆?DHEA?また「あるある」か!?

スーパーの一角が空っぽでビビッたぜ。どうやら「あるある効果」らしい。どうせなら、白菜を「あるある大辞典」で特集していただきたいものだね。

まぁ、それはそれで、DHEAで痩せるらしい。毛も生えるらしいwww

とりあえず、DHEAはホルモンだ。それも体内でももっとも豊富なステロイドホルモン。ステロイドには副作用があるんだよね。

http://en.wikipedia.org/wiki/Dehydroepiandrosterone

http://www.quackwatch.org/01QuackeryRelatedTopics/dhea.html

In the court of media and public opinion, DHEA is king, a pill that can help us live longer, lose weight or gain it, prevent cancer, heart disease, and Alzheimer's, and combat AIDS and other infectious diseases. The crescendo of praise for this hormone has drowned out the serious cautions that top researchers in the field are raising:

"The one thing you should tell your readers is that we know very little about DHEA. The hype is out of control, and I can't stress enough that it should be used with caution, if at all, until we know more," says Samuel Yen, MD, professor of reproductive medicine at the University of California, San Diego. News reports and advertisements widely cite his studies of people who took DHEA supplements for three months as proof that the hormone "works."

"No one should take DHEA except under the supervision of a physician, who should routinely check steroid and cholesterol levels, glucose tolerance, and prostate health in men," says John Nestle, MD, professor of endocrinology and metabolism at Virginia Commonwealth University, who studies DHEA's effects on diabetes and blood clotting.

"DHEA is the snake oil of the '90s. It makes me very nervous that people are using a drug we don't know anything about. I won't recommend it," says Elizabeth Barrett-Connor, MD, professor and chair, department of family and preventive medicine at the University of California, San Diego. Her studies of natural DHEA levels in older people suggest that higher levels may protect men against heart disease.

"Selling potent steroid hormones in health food stores or by mail could be a disaster in the making. DHEA should be classified as an investigational drug and used only in clinical research until we figure out what it does and its side effects," says Peter Hornsby, PhD, associate professor of cell biology at Baylor College of Medicine. His team has just identified the body's DHEA-making cells.

権威大好きな諸君に朗報だ!スゲー肩書きをもったオジサマ方がDHEAの素晴らしさを説いてくださっているぞ!訳すの面倒だが、つまるところ「がまの油より効果がないくせに、副作用がバリバリある」副腎皮質ホルモンってことだな。

Much of the popular and scientific interest in DHEA stems from our culture's emphasis on youth. If levels of this hormone decline with age, the thinking goes, we could avoid the health problems that accompany aging -- or even extend our lifespan -- by keeping DHEA levels high. Many people are already taking DHEA just in case this turns out to be true. That wouldn't be a problem if this substance were as safe as vitamin C. But as a potent steroid hormone, DHEA has the potential for far-reaching side effects throughout the body. . . .

With DHEA and aging, there are no proven benefits and some potentially serious risks. Yet people are flocking to use this virtually unregulated substance, which troubles HealthNews associate editor Arthur Feinberg, MD.

"The potential for irreversible side effects is real," he says. "So given that there's no convincing evidence for any benefit of DHEA, I feel strongly that people should not take it."

DHEAが本当に効くのかは分かってない。確固たる証拠なし。でも、不可逆な副作用の可能性はある。だから、摂取するべきものではない。

Over the past two years, I have come across many cases of heart-rhythym disturbances associated with high-dose use of DHEA and pregnenolone. I reported one such case in a man taking 50 mg per day in the October 1998 issue of the Annals of Internal Medicine (volume 129, page 588). Other side effects include acne, unwanted hair growth, scalp hair loss, menstrual irregularities, irritability, and aggression. In my opinion, DHEA, androstenedione, or pregnenolone should not be sold over the counter in doses greater than 5 mg.

50mg以上の摂取で可能性がある副作用――不整脈、にきび、多毛症、頭髪抜けて、精神的にダウンする、と。

つまり、前のと合わせると…「一度抜けた毛は摂取を止めても生えてこない」ってことか?それが "irreversible" の意図?

っつーか、「運動」でもDHEAは増えるそうですってよ、奥さん!それに、納豆2回も食うのかよ?!他の穀物が食えなくなるじゃん……。まぁ、納豆ぐらいならいいけど、DHEAのサプリメントには手を出さない方が賢明だと思いますね。